Genomic landscape of salivary gland tumors.
نویسندگان
چکیده
منابع مشابه
Genomic landscape of salivary gland tumors
Effective treatment options for advanced salivary gland tumors are lacking. To better understand these tumors, we report their genomic landscape. We studied the molecular aberrations in 117 patients with salivary gland tumors that were, on physician request, tested in a Clinical Laboratory Improvement Amendments (CLIA) laboratory (Foundation Medicine, Cambridge, MA) using next-generation sequen...
متن کاملA Review of Signet Ring cells in Salivary Gland Tumors
Objectives: Signet Ring Cells (SRCs) are often seen in gastrointestinal, breast, bile duct and lung invasive carcinomas. Observing these cells in benign and malignant lesions of the salivary glands is not common. Signet-ring cell adenocarcinoma is rare and is commonly seen in the secondary salivary glands. Although, the presence of SRCs in other neoplasms of the body is usually associated with ...
متن کاملMalignant salivary gland tumors
Salivary gland neoplasms are a heterogeneous and important group of tumors of the Oral and Maxillofacial Pathology. They comprise from 2 to 3% of all the salivary gland lesions and tumors1,2 because their heterogeneity, since several years, different classifications based in clinical or microscopic criteria had been appeared.3-7 The most recent and most widely used is that proposed by Seifert e...
متن کاملD-1 Gene Polymorphism in Salivary Gland Tumors
Objectives This study aimed to assess PD-1gene polymorphism in salivary gland tumors in patients referred to Khalili Hospital in Shiraz. Methods This case-control study evaluated 48 patients with salivary gland tumors and 100 age- and sex-matched healthy controls. First, 5cc blood samples were obtained from patients and transferred to vials containing anti-coagulated EDTA. DNA was extracted, a...
متن کاملMTA1 Expression in Benign and Malignant Salivary gland Tumors
Introduction: Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Oncology
سال: 2015
ISSN: 0732-183X,1527-7755
DOI: 10.1200/jco.2015.33.15_suppl.6056